OrthologID automates gene orthology determination within a character-based phylogenetic framework.
OrthologID Online identifies orthologous groups for complete genomes compiled in our database (Orthologous Group Search), and classifies user-input query sequences into orthologous groups generated from complete genomes (Query Orthology Classification). It identifies diagnostic characters that define each orthologous group, as well as diagnostic characters responsible for classifying query sequences. The output is presented in phylogenetic tree format.
Joanna C. Chiu, Ernest K. Lee, Mary G. Egan, Indra Neil Sarkar, Gloria M. Coruzzi, and Rob DeSalle. OrthologID: automation of genome-scale ortholog identification within a parsimony framework Bioinformatics (2006) 22(6): 699-707 first published online January 12, 2006 doi:10.1093/bioinformatics/btk040
This site uses an early version of the OrthologID Plant database and pipeline. To install the latest version of the OrthologID pipeline on your own cluster, follow the instructions here to download the source code from our Mercurial repository.